maverick_ncsu, it is possible that Hess could ref a NCAA game. Absolutely. Could he ref a game involving an ACC school? Absolutely.
Since they are independent contractors, the NCAA selects the officials. Would the NCAA put Hess in a game involving an ACC school? I seriously doubt it.
For your second question, you have that backwards. At least for the Power 5 conferences, referees are traditionally from the road team’s conference, just like in football.
But seeing as the AAC among other conferences are reviewing Hess as a ref now, there is a good chance he will not be refereeing anymore.